Visualizing cell function dynamics in virtual outer space – Publicly Invited Research 2018－2019

  1. A01 Ogura
  2. A01 H. Takahashi
  3. A01 S. Takahashi
  4. A01 Michiue
  5. A01 Hinoi
  6. A01 Tsumoto
  7. A01 Nikawa
  8. A01 Chatani
  9. A01 Kawakami
  10. A01 Akiyama
  11. A01 Tomita
  1. A02 Shinohara
  2. A02 Mieda
  3. A02 Maekawa
  4. A02 Abe
  5. A02 Ohgami
  6. A02 Kawano
  7. A02 Takano
  1. A03 Suzuki
  2. A03 Nakamura
  3. A03 Harada
  4. A03 Kobayashi
  5. A03 Miyamoto
  6. A03 Funayama
  7. A03 Kakinuma
  1. B01 Lazarus
  2. B01 Kato
  3. B01 Kunieda
  4. B01 Kitaya
  5. B01 Sawano
Research Subject Visualizing cell function dynamics in virtual outer space
Research Group Leader
name
Asako Sakaue-Sawano
Laboratory for Cell Function Dynamics, Center for Brain Science, RIKEN
Website
http://cfds.brain.riken.jp/Fucci.html
Research Collaborator(s)
  • Takamasa Yoshida
    Department of Biomedical Engineering, Faculty of Science and Engineering, Toyo University

The purpose of this research is to better understand the effects of gravity and space radiation on the cellular homeostasis by employing Direct Visualization technology. We actually have been doing assemble several devices, such as 3D-clinostat and miniature light microscopy, to develop novel experimental systems, where mammalian cells expressing a variety of fluorescent probes (e.g. Fucci, oxidative stress probe, autophagy probe, inflammation probe, metabolic probe) are time-lapse imaged while exposed to micro- and hyper-gravity or space radiation. Our study will provide valuable suggestions about how the humankind can spend healthy life in real outer space.