2016-2017 Publicly Invited Research

A01 Molecular and Cellular Foundations of Gravity Responses

Research Subject Effects of gravity changes on thymic microenvironments
Research Group Leader
  • Taishin Akiyama
    Associate Professor, The Institute of Medical Science, The University of Tokyo
Research Subject Mechanisms of skeletal muscle homeostasis maintenance through crosstalk between the sensory nervous system and skeletal muscle satellite cells
Research Group Leader
Research Subject Identification of the gravity sensory system in bone homeostasis in medaka
Research Group Leader
  • Masahiro Chatani
    Assistant Professor, Department of Pharmacology, School of Dentistry, Showa University
Research Subject Elucidation of the molecular mechanism underlying gravity-YAP-mediated 3D organogenesis -Toward generating a complex 3D organ in microgravity-
Research Group Leader
Research Subject Pathophysiological role of mitochondrial aconitase in unloading-mediated muscle atrophy
Research Group Leader
Research Subject Study on effects of the space environment on brain structures and functions of model vertebrate zebrafish
Research Group Leader
  • Koichi Kawakami
    Professor, National Institute of Genetics
Research Subject Mechanism of homeostatic robustness by exercise to reduce health risk in space life
Research Group Leader
  • Takuro Numaga-Tomita
    Assistant professor, Okazaki Institute for Integrative Biology (National Institute for Physiological Sciences), National institutes of Natural Sciences
Research Subject Study for aging of C. elegans in space
Research Group Leader
  • Yoko Honda
    Research Fellow, Center for Advanced Biomedical Sciences, Research Institute for Science and Engineering, Waseda University)

A02 Influence of a Prolonged Stay in Space on Higher-order Homeostasis

Research Subject Mechanisms underlying bone loss during spaceflight ~Elucidation of the regulatory mechanism for expression of an osteoclast differentiation factor, RANKL
Research Group Leader
  • Masahiro Shinohara
    Junior Associate Professor, Department of Systems BioMedicine, Tokyo Medical and Dental University
Research Subject Immune System Plasticity and Failure in Response to Gravitational Changes - An Approach to Understanding Immunological Memory -
Research Group Leader
  • Yoichi Maekawa
    Professor, Graduate School of Medicine, Gifu University
Research Subject Development of risk assessment and method of protection for inner ear impairment caused by possible physical stress in a closed space
Research Group Leader
  • Nobutaka Ohgami
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine
Research Subject Effects of Confinement Stress on Homeostasis of the Mammalian Endocrine System and Metabolism
Research Group Leader
  • Wataru Nishimura
    Associate Professor, Department of Anatomy, Bio-imaging and Neuro-cell Science, Jichi Medical University
    (*Written in Japanese)
Research Subject Epigenetic mechanisms understanding the responsiveness of skeletal muscles to physiological stimuli during an ultra-long-term stay in space
Research Group Leader
Research Subject Effectiveness of Artificial Gravity with Exercise on Spaceflight Deconditioning in Humans
Research Group Leader
  • Satoshi Iwase
    Professor, Department of Physiology, Aichi Medical University School of Medicine
Research Subject Investigation of core technology for the food production in closed space under microgravity
Research Group Leader
  • Takuya Furuichi
    Associate Professor, Graduate School of Human Life Sciences, Nagoya University of Economics
Research Subject Chronic effects of non-24 hour solar days
Research Group Leader
  • Jihwan Myung
    Research Scientist, Okinawa Institute of Science and Technology Graduate University
Research Subject Understanding the health effects and susceptibility factors of circadian misalignment
Research Group Leader
  • Shingo Kitamura
    Section Chief, Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry

A03 Environmental Risks Expected in Space

Research Subject Development of novel PDMS-based micro-nano device for monitoring DNA damage
Research Group Leader
Research Subject Differences in Radiation-induced DNA Damage Responses among Organs; Spatiotemporal Analyses Using Genetically Engineered Mice
Research Group Leader
Research Subject Biological Effects of Clustered DNA Damage Induced by Space Radiation
Research Group Leader
Research Subject Investigation of molecular mechanisms underlying the alterations in host-pathogen interaction during spaceflight
Research Group Leader
  • Mutsunori Shirai
    Professor, Vice-president, Department of Microbiology and Immunology, Yamaguchi University Graduate School of Medicine
Research Subject Estimation of carcinogenic risk after exposure to space radiation by pathological and genomic analyses
Research Group Leader
  • Shizuko Kakinuma
    Director, Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology

B01 Cross-sectional/complementary studies

Research Subject Hypothermia as a risk factor for memory consolidation
Research Group Leader
  • Michael Lazarus
    Associate Professor, International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba
Research Subject Establishment of model mice for non-invasive monitoring of physiological effects in extreme environments
Research Group Leader
Research Subject Elucidation of molecular machinery essential for extremotolerant ability in tardigrades
Research Group Leader
Research Subject Understanding the Mechanism of Maintaining Social Regulatory Functions under Unexpected Stress
Research Group Leader
  • Koji Shimada
    Specially-appointed Assistant Professor, Research Center for Child Mental Development, University of Fukui
Research Subject Plant culture system for producing food, recycling materials and maintaining human health necessary for life support in space
Research Group Leader
  • Yoshiaki Kitaya
    Professor, Graduate School of Life and Environmental Sciences, Osaka Prefecture University
Research Subject Visualizing cell function dynamics in virtual outer space
Research Group Leader